Autoimmune disease

Aberrant functioning of T lymphocytes is the basis of autoimmune disease and T cell leukaemia. NTRC scientists have developed a series of highly selective inhibitors of T cell activity.

T lymphocytes are a critical component of the acquired immune system, while aberrant T cell functioning is the basis of autoimmune diseases, such as rheumatoid arthritis and psoriasis, T cell leukaemia. NTRC has developed a series of highly selective inhibitors of T cell activity using its ResidenceTimerâ„¢ platform. The compounds are active in specific T cell assays, including human whole blood, have good oral bioavailability and have shown potent in vivo activity in several models of human disease. If you are interested to learn more about this project, contact us.

Current Projects

Autoimmune disease