Full Kinase Panel

Kinome-Tree-Quickscout-Full-Panel_smallThrough our partner Carna Biosciences we are offering the Full Kinase Panel. This panel is comprised of all the kinase assays available at Carna Biosciences, currently more than 300 assays. Clients can either choose to run the full panel or can ‘cherry-pick’ their most preferred kinases.

https://www.ntrc.nl/wp-content/uploads/2014/02/Kinome-Tree-Full-Panel_21.jpg
Kinases Available in the Full Kinase panel

The Full Kinase Panel -available at Carna- enables clients to extensively profile their compounds on almost the entire kinome. The full kinase panel is run with high accuracy and a rapid turn-around time of 4 weeks with intermediate reporting at 2 weeks.

Target Name

Group

Assay Type

Source

(Carna Cat No.)

ABL (ABL1)

TK

Mobility Shift, IMAPTM

08-001

ABL (ABL1) [E255K]

TK

Mobility Shift, IMAPTM

08-094

ABL (ABL1) [T315I]

TK

Mobility Shift, IMAPTM

08-093

ACK (TNK2)

TK

Mobility Shift, IMAPTM

08-196

AKT1

STK

Mobility Shift, IMAPTM

01-101

AKT2

STK

Mobility Shift, IMAPTM

01-102

AKT3

STK

Mobility Shift, IMAPTM

01-103

ALK

TK

Mobility Shift, IMAPTM

08-518

ALK[F1174L]

TK

Mobility Shift, IMAPTM

08-519

ALK[L1196M]

TK

Mobility Shift, IMAPTM

08-529

ALK[R1275Q]

TK

Mobility Shift, IMAPTM

08-520

AMPKα1/β1/γ1 (PRKAA1/B1/G1)

STK

Mobility Shift, IMAPTM

02-113

AMPKα2/β1/γ1 (PRKAA2/B1/G1)

STK

Mobility Shift, IMAPTM

02-114

ARG (ABL2)

TK

Mobility Shift, IMAPTM

08-102

AurA (AURKA)

STK

Mobility Shift, IMAPTM

05-101

AurA(AURKA)/TPX2

STK

Mobility Shift, IMAPTM

05-186

AurB (AURKB)/INCENP

STK

Mobility Shift, IMAPTM

05-102

AurC (AURKC)

STK

Mobility Shift, IMAPTM

05-103

AXL

TK

Mobility Shift, IMAPTM

08-107

BLK

TK

Mobility Shift, IMAPTM

08-164

BMPR1A

STK

ELISA

09-137

BMX

TK

Mobility Shift, IMAPTM

08-179

BRAF

STK

ELISA

09-122

BRAF

STK

Mobility Shift, IMAPTM

09-122

BRAF [V600E]

STK

ELISA

09-144

BRAF[V600E]

STK

Mobility Shift, IMAPTM

09-144

BRK (PTK6)

TK

Mobility Shift, IMAPTM

08-165

BRSK1

STK

Mobility Shift, IMAPTM

02-115

BRSK2

STK

Mobility Shift, IMAPTM

02-116

BTK

TK

Mobility Shift, IMAPTM

08-080

CaMK1α (CAMK1)

STK

Mobility Shift, IMAPTM

02-104

CaMK1δ (CAMK1D)

STK

Mobility Shift, IMAPTM

02-106

CaMK2α (CAMK2A)

STK

Mobility Shift, IMAPTM

02-109

CaMK2β (CAMK2B)

STK

Mobility Shift, IMAPTM

02-110

CaMK2γ (CAMK2G)

STK

Mobility Shift, IMAPTM

02-112

CaMK2δ (CAMK2D)

STK

Mobility Shift, IMAPTM

02-111

CaMK4

STK

Mobility Shift, IMAPTM

02-108

CDC2 /CycB1

STK

Mobility Shift, IMAPTM

04-102

CDC7/ASK

STK

Mobility Shift, IMAPTM

05-109

CDK2 /CycA2

STK

Mobility Shift, IMAPTM

04-103

CDK2 /CycE1

STK

Mobility Shift, IMAPTM

04-165

CDK3 /CycE1

STK

Mobility Shift, IMAPTM

04-104

CDK4 /CycD3

STK

Mobility Shift, IMAPTM

04-105

CDK5 /p25

STK

Mobility Shift, IMAPTM

04-106

CDK6 /CycD3

STK

Mobility Shift, IMAPTM

04-107

CDK7 /CycH/MAT1

STK

Mobility Shift, IMAPTM

04-108

CDK9 /CycT1

STK

Mobility Shift, IMAPTM

04-110

CGK2 (PRKG2)

STK

Mobility Shift, IMAPTM

01-143

CHK1 (CHEK1)

STK

Mobility Shift, IMAPTM

02-117

CHK2 (CHEK2)

STK

Mobility Shift, IMAPTM

02-162

CK1α (CSNK1A1)

STK

Mobility Shift, IMAPTM

03-101

CK1γ1 (CSNK1G1)

STK

Mobility Shift, IMAPTM

03-105

CK1γ2 (CSNK1G2)

STK

Mobility Shift, IMAPTM

03-106

CK1γ3 (CSNK1G3)

STK

Mobility Shift, IMAPTM

03-107

CK1δ (CSNK1D)

STK

Mobility Shift, IMAPTM

03-103

CK1ε (CSNK1E)

STK

Mobility Shift, IMAPTM

03-104

CK2α1/β (CSNK2A1/B)

STK

Mobility Shift, IMAPTM

05-184

CK2α2/β (CSNK2A2/B)

STK

Mobility Shift, IMAPTM

05-185

CLK1

STK

Mobility Shift, IMAPTM

04-126

CLK2

STK

Mobility Shift, IMAPTM

04-127

CLK3

STK

Mobility Shift, IMAPTM

04-128

COT (MAP3K8)

STK

Mobility Shift, IMAPTM

07-301

COT(MAP3K8)

STK

ELISA

07-301

CRIK (CIT)

STK

Mobility Shift, IMAPTM

01-104

CSK

TK

Mobility Shift, IMAPTM

08-111

DAPK1

STK

Mobility Shift, IMAPTM

02-134

DCAMKL2

STK

Mobility Shift, IMAPTM

02-140

DDR1

TK

Mobility Shift, IMAPTM

08-113

DDR2

TK

Mobility Shift, IMAPTM

08-114

DLK (MAP3K12)

STK

Mobility Shift, IMAPTM

09-111

DLK(MAP3K12)

STK

ELISA

09-111

DYRK1A

STK

Mobility Shift, IMAPTM

04-130

DYRK1B

STK

Mobility Shift, IMAPTM

04-131

DYRK2

STK

Mobility Shift, IMAPTM

04-132

DYRK3

STK

Mobility Shift, IMAPTM

04-133

EEF2K

STK

Mobility Shift, IMAPTM

10-113

EGFR

TK

Mobility Shift, IMAPTM

08-115

EGFR[d746-750/T790M]

TK

Mobility Shift, IMAPTM

08-528

EGFR[d746-750]

TK

Mobility Shift, IMAPTM

08-527

EGFR[L858R]

TK

Mobility Shift, IMAPTM

08-502

EGFR[L861Q]

TK

Mobility Shift, IMAPTM

08-513

EGFR[T790M/L858R]

TK

Mobility Shift, IMAPTM

08-510

EGFR[T790M]

TK

Mobility Shift, IMAPTM

08-194

EML4-ALK

TK

Mobility Shift, IMAPTM

08-516

EPHA1

TK

Mobility Shift, IMAPTM

08-119

EPHA2

TK

Mobility Shift, IMAPTM

08-121

EPHA3

TK

Mobility Shift, IMAPTM

08-122

EPHA4

TK

Mobility Shift, IMAPTM

08-123

EPHA5

TK

Mobility Shift, IMAPTM

08-124

EPHA6

TK

Mobility Shift, IMAPTM

08-125

EPHA7

TK

Mobility Shift, IMAPTM

08-126

EPHA8

TK

Mobility Shift, IMAPTM

08-127

EPHB1

TK

Mobility Shift, IMAPTM

08-128

EPHB2

TK

Mobility Shift, IMAPTM

08-129

EPHB3

TK

Mobility Shift, IMAPTM

08-130

EPHB4

TK

Mobility Shift, IMAPTM

08-131

Erk1 (MAPK3)

STK

Mobility Shift, IMAPTM

04-142

Erk2 (MAPK1)

STK

Mobility Shift, IMAPTM

04-143

Erk5 (MAPK7)

STK

Mobility Shift, IMAPTM

04-146

FAK (PTK2)

TK

Mobility Shift, IMAPTM

08-137

FER

TK

Mobility Shift, IMAPTM

08-139

FES

TK

Mobility Shift, IMAPTM

08-140

FGFR1

TK

Mobility Shift, IMAPTM

08-133

FGFR1[V561M]

TK

Mobility Shift, IMAPTM

08-536

FGFR2

TK

Mobility Shift, IMAPTM

08-134

FGFR3

TK

Mobility Shift, IMAPTM

08-135

FGFR3[K650E]

TK

Mobility Shift, IMAPTM

08-501

FGFR3[K650M]

TK

Mobility Shift, IMAPTM

08-199

FGFR4

TK

Mobility Shift, IMAPTM

08-136

FGFR4[N535K]

TK

Mobility Shift, IMAPTM

08-524

FGFR4[V550E]

TK

Mobility Shift, IMAPTM

08-525

FGFR4[V550L]

TK

Mobility Shift, IMAPTM

08-526

FGR

TK

Mobility Shift, IMAPTM

08-166

FLT1

TK

Mobility Shift, IMAPTM

08-189

FLT3

TK

Mobility Shift, IMAPTM

08-154

FLT4

TK

Mobility Shift, IMAPTM

08-190

FMS (CSF1R)

TK

Mobility Shift, IMAPTM

08-155

FRK

TK

Mobility Shift, IMAPTM

08-167

FYN

TK

Mobility Shift, IMAPTM

08-068

GSK3α (GSK3A)

STK

Mobility Shift, IMAPTM

04-140

GSK3β (GSK3B)

STK

Mobility Shift, IMAPTM

04-141

Haspin (GSG2)

STK

Mobility Shift, IMAPTM

05-111

HCK

TK

Mobility Shift, IMAPTM

08-169

HER2 (ERBB2)

TK

Mobility Shift, IMAPTM

08-016

HER4 (ERBB4)

TK

Mobility Shift, IMAPTM

08-118

HGK (MAP4K4)

STK

Mobility Shift, IMAPTM

07-137

HIPK1

STK

Mobility Shift, IMAPTM

04-135

HIPK2

STK

Mobility Shift, IMAPTM

04-136

HIPK3

STK

Mobility Shift, IMAPTM

04-137

HIPK4

STK

Mobility Shift, IMAPTM

04-138

IGF1R

TK

Mobility Shift, IMAPTM

08-141

IKKα (CHUK)

STK

Mobility Shift, IMAPTM

05-112

IKKβ (IKBKB)

STK

Mobility Shift, IMAPTM

05-084

IKKε (IKBKE)

STK

Mobility Shift, IMAPTM

05-114

INSR

TK

Mobility Shift, IMAPTM

08-142

IRAK1

STK

Mobility Shift, IMAPTM

09-101

IRAK4

STK

Mobility Shift, IMAPTM

09-145

IRR (INSRR)

TK

Mobility Shift, IMAPTM

08-143

ITK

TK

Mobility Shift, IMAPTM

08-181

JAK1

TK

Mobility Shift, IMAPTM

08-144

JAK2

TK

Mobility Shift, IMAPTM

08-045

JAK3

TK

Mobility Shift, IMAPTM

08-046

JNK1 (MAPK8)

STK

Mobility Shift, IMAPTM

04-163

JNK2 (MAPK9)

STK

Mobility Shift, IMAPTM

04-164

JNK3 (MAPK10)

STK

Mobility Shift, IMAPTM

04-150

KDR

TK

Mobility Shift, IMAPTM

08-191

KIT

TK

Mobility Shift, IMAPTM

08-156

KIT[D816V]

TK

Mobility Shift, IMAPTM

08-505

KIT[T670I]

TK

Mobility Shift, IMAPTM

08-195

KIT[V560G]

TK

Mobility Shift, IMAPTM

08-504

KIT[V654A]

TK

Mobility Shift, IMAPTM

08-511

LATS2

STK

Mobility Shift, IMAPTM

01-124

LCK

TK

Mobility Shift, IMAPTM

08-170

LIMK1

STK

ELISA

09-105

LKB1(STK11)/MO25α/STRADα

STK

ELISA

02-119

LOK (STK10)

STK

Mobility Shift, IMAPTM

07-315

LTK

TK

Mobility Shift, IMAPTM

08-106

LYNa

TK

Mobility Shift, IMAPTM

08-171

LYNb

TK

Mobility Shift, IMAPTM

08-172

MAP2K1

STK

ELISA

07-041

MAP2K1

STK

Mobility Shift, IMAPTM

07-141

MAP2K2

STK

ELISA

07-042

MAP2K2

STK

Mobility Shift, IMAPTM

07-142

MAP2K3

STK

ELISA

07-048

MAP2K3

STK

Mobility Shift, IMAPTM

07-143

MAP2K4

STK

ELISA

07-044

MAP2K4

STK

Mobility Shift, IMAPTM

07-144

MAP2K5

STK

ELISA

07-145

MAP2K5

STK

Mobility Shift, IMAPTM

07-145

MAP2K6

STK

ELISA

07-046

MAP2K6

STK

Mobility Shift, IMAPTM

07-146

MAP2K7

STK

ELISA

07-047

MAP2K7

STK

Mobility Shift, IMAPTM

07-148

MAP3K1

STK

ELISA

07-103

MAP3K1

STK

Mobility Shift, IMAPTM

07-103

MAP3K2

STK

ELISA

07-004

MAP3K2

STK

Mobility Shift, IMAPTM

07-104

MAP3K3

STK

ELISA

07-105

MAP3K3

STK

Mobility Shift, IMAPTM

07-105

MAP3K4

STK

ELISA

07-106

MAP3K4

STK

Mobility Shift, IMAPTM

07-106

MAP3K5

STK

ELISA

07-107

MAP3K5

STK

Mobility Shift, IMAPTM

07-107

MAP4K2

STK

Mobility Shift, IMAPTM

07-111

MAPKAPK2

STK

Mobility Shift, IMAPTM

02-142

MAPKAPK3

STK

Mobility Shift, IMAPTM

02-143

MAPKAPK5

STK

Mobility Shift, IMAPTM

02-144

MARK1

STK

Mobility Shift, IMAPTM

02-120

MARK2

STK

Mobility Shift, IMAPTM

02-121

MARK3

STK

Mobility Shift, IMAPTM

02-122

MARK4

STK

Mobility Shift, IMAPTM

02-123

MELK

STK

Mobility Shift, IMAPTM

02-124

MER (MERTK)

TK

Mobility Shift, IMAPTM

08-108

MET

TK

Mobility Shift, IMAPTM

08-151

MET[Y1235D]

TK

Mobility Shift, IMAPTM

08-198

MGC42105

STK

Mobility Shift, IMAPTM

02-125

MINK (MINK1)

STK

Mobility Shift, IMAPTM

07-139

MLK1 (MAP3K9)

STK

Mobility Shift, IMAPTM

09-115

MLK1(MAP3K9)

STK

ELISA

09-015

MLK2 (MAP3K10)

STK

Mobility Shift, IMAPTM

09-116

MLK2(MAP3K10)

STK

ELISA

09-116

MLK3 (MAP3K11)

STK

Mobility Shift, IMAPTM

09-017

MLK3(MAP3K11)

STK

ELISA

09-017

MNK1 (MKNK1)

STK

Mobility Shift, IMAPTM

02-145

MNK2 (MKNK2)

STK

Mobility Shift, IMAPTM

02-146

MOS

STK

ELISA

05-118

MOS

STK

Mobility Shift, IMAPTM

05-118

MRCKα (CDC42BPA)

STK

Mobility Shift, IMAPTM

01-107

MRCKβ (CDC42BPB)

STK

Mobility Shift, IMAPTM

01-108

MSK1 (RPS6KA5)

STK

Mobility Shift, IMAPTM

01-147

MSK2 (RPS6KA4)

STK

Mobility Shift, IMAPTM

01-148

MSSK1 (STK23)

STK

Mobility Shift, IMAPTM

04-159

MST1 (STK4)

STK

Mobility Shift, IMAPTM

07-116

MST2 (STK3)

STK

Mobility Shift, IMAPTM

07-117

MST3 (STK24)

STK

Mobility Shift, IMAPTM

07-118

MST4

STK

Mobility Shift, IMAPTM

07-119

MUSK

TK

Mobility Shift, IMAPTM

08-153

NDR1 (STK38)

STK

Mobility Shift, IMAPTM

01-125

NDR2 (STK38L)

STK

Mobility Shift, IMAPTM

01-126

NEK1

STK

Mobility Shift, IMAPTM

05-123

NEK2

STK

Mobility Shift, IMAPTM

05-226

NEK4

STK

Mobility Shift, IMAPTM

05-128

NEK6

STK

Mobility Shift, IMAPTM

05-130

NEK7

STK

Mobility Shift, IMAPTM

05-131

NEK9

STK

Mobility Shift, IMAPTM

05-133

NPM1-ALK

TK

Mobility Shift, IMAPTM

08-517

NuaK1

STK

Mobility Shift, IMAPTM

02-126

NuaK2

STK

Mobility Shift, IMAPTM

02-127

p38α (MAPK14)

STK

Mobility Shift, IMAPTM

04-152

p38β (MAPK11)

STK

Mobility Shift, IMAPTM

04-153

p38γ (MAPK12)

STK

Mobility Shift, IMAPTM

04-155

p38δ (MAPK13)

STK

Mobility Shift, IMAPTM

04-154

p70S6K (RPS6KB1)

STK

Mobility Shift, IMAPTM

01-154

p70S6Kβ (RPS6KB2)

STK

Mobility Shift, IMAPTM

01-155

PAK1

STK

Mobility Shift, IMAPTM

07-123

PAK2

STK

Mobility Shift, IMAPTM

07-124

PAK3

STK

Mobility Shift, IMAPTM

07-125

PAK4

STK

Mobility Shift, IMAPTM

07-126

PAK5 (PAK7)

STK

Mobility Shift, IMAPTM

07-127

PAK6

STK

Mobility Shift, IMAPTM

07-128

PASK

STK

Mobility Shift, IMAPTM

02-128

PBK

STK

Mobility Shift, IMAPTM

05-168

PDGFRα (PDGFRA)

TK

Mobility Shift, IMAPTM

08-157

PDGFRα (PDGFRA) [T674I]

TK

Mobility Shift, IMAPTM

08-503

PDGFRα (PDGFRA) [V561D]

TK

Mobility Shift, IMAPTM

08-507

PDGFRβ (PDGFRB)

TK

Mobility Shift, IMAPTM

08-158

PDHK2 (PDK2)

STK

Mobility Shift, IMAPTM

10-140

PDHK4 (PDK4)

STK

Mobility Shift, IMAPTM

10-125

PDK1 (PDPK1)

STK

Mobility Shift, IMAPTM

01-132

PEK (EIF2AK3)

STK

Mobility Shift, IMAPTM

05-155

PGK (PRKG1)

STK

Mobility Shift, IMAPTM

01-142

PHKG1

STK

Mobility Shift, IMAPTM

02-152

PHKG2

STK

Mobility Shift, IMAPTM

02-153

PIK3CA/PIK3R1

Lipid

Mobility Shift, IMAPTM

11-101

PIM1

STK

Mobility Shift, IMAPTM

02-054

PIM2

STK

Mobility Shift, IMAPTM

02-155

PIM3

STK

Mobility Shift, IMAPTM

02-156

PKACα (PRKACA)

STK

Mobility Shift, IMAPTM

01-127

PKACβ (PRKACB)

STK

Mobility Shift, IMAPTM

01-128

PKACγ (PRKACG)

STK

Mobility Shift, IMAPTM

01-129

PKCα (PRKCA)

STK

Mobility Shift, IMAPTM

01-133

PKCβ1 (PRKCB1)

STK

Mobility Shift, IMAPTM

01-134

PKCβ2 (PRKCB2)

STK

Mobility Shift, IMAPTM

01-165

PKCγ (PRKCG)

STK

Mobility Shift, IMAPTM

01-137

PKCδ (PRKCD)

STK

Mobility Shift, IMAPTM

01-135

PKCε (PRKCE)

STK

Mobility Shift, IMAPTM

01-136

PKCζ (PRKCZ)

STK

Mobility Shift, IMAPTM

01-141

PKCη (PRKCH)

STK

Mobility Shift, IMAPTM

01-138

PKCθ (PRKCQ)

STK

Mobility Shift, IMAPTM

01-140

PKCι (PRKCI)

STK

Mobility Shift, IMAPTM

01-139

PKD1 (PRKD1)

STK

Mobility Shift, IMAPTM

02-157

PKD2 (PRKD2)

STK

Mobility Shift, IMAPTM

02-158

PKD3 (PRKD3)

STK

Mobility Shift, IMAPTM

02-159

PKN1

STK

Mobility Shift, IMAPTM

01-144

PKR (EIF2AK2)

STK

Mobility Shift, IMAPTM

05-156

PLK1

STK

Mobility Shift, IMAPTM

05-157

PLK2

STK

Mobility Shift, IMAPTM

05-158

PLK3

STK

Mobility Shift, IMAPTM

05-159

PRKX

STK

Mobility Shift, IMAPTM

01-130

PYK2 (PTK2B)

TK

Mobility Shift, IMAPTM

08-138

QIK (SNF1LK2)

STK

Mobility Shift, IMAPTM

02-129

RAF1

STK

ELISA

09-125

RAF1

STK

Mobility Shift, IMAPTM

09-125

RET

TK

Mobility Shift, IMAPTM

08-159

RET[G691S]

TK

Mobility Shift, IMAPTM

08-522

RET[M918T]

TK

Mobility Shift, IMAPTM

08-508

RET[S891A]

TK

Mobility Shift, IMAPTM

08-523

RET[Y791F]

TK

Mobility Shift, IMAPTM

08-521

ROCK1

STK

Mobility Shift, IMAPTM

01-109

ROCK2

STK

Mobility Shift, IMAPTM

01-110

RON (MST1R)

TK

Mobility Shift, IMAPTM

08-152

ROS (ROS1)

TK

Mobility Shift, IMAPTM

08-163

RSK1 (RPS6KA1)

STK

Mobility Shift, IMAPTM

01-149

RSK2 (RPS6KA3)

STK

Mobility Shift, IMAPTM

01-150

RSK3 (RPS6KA2)

STK

Mobility Shift, IMAPTM

01-151

RSK4 (RPS6KA6)

STK

Mobility Shift, IMAPTM

01-152

SGK

STK

Mobility Shift, IMAPTM

01-158

SGK2

STK

Mobility Shift, IMAPTM

01-159

SGK3 (SGKL)

STK

Mobility Shift, IMAPTM

01-160

SIK (SNF1LK)

STK

Mobility Shift, IMAPTM

02-131

skMLCK (MYLK2)

STK

Mobility Shift, IMAPTM

02-150

SLK

STK

Mobility Shift, IMAPTM

07-129

SPHK1

Lipid

Mobility Shift, IMAPTM

11-105

SPHK2

Lipid

Mobility Shift, IMAPTM

11-106

SRC

TK

Mobility Shift, IMAPTM

08-173

SRM (SRMS)

TK

Mobility Shift, IMAPTM

08-174

SRPK1

STK

Mobility Shift, IMAPTM

04-160

SRPK2

STK

Mobility Shift, IMAPTM

04-161

SYK

TK

Mobility Shift, IMAPTM

08-176

TAK1-TAB1 (MAP3K7)

STK

Mobility Shift, IMAPTM

09-019

TAK1-TAB1(MAP3K7)

STK

ELISA

09-019

TAOK2

STK

Mobility Shift, IMAPTM

07-133

TBK1

STK

Mobility Shift, IMAPTM

05-115

TEC

TK

Mobility Shift, IMAPTM

08-182

TIE2 (TEK)

TK

Mobility Shift, IMAPTM

08-185

TNIK

STK

Mobility Shift, IMAPTM

07-138

TNK1

TK

Mobility Shift, IMAPTM

08-104

TRKA (NTRK1)

TK

Mobility Shift, IMAPTM

08-186

TRKB (NTRK2)

TK

Mobility Shift, IMAPTM

08-187

TRKC (NTRK3)

TK

Mobility Shift, IMAPTM

08-197

TSSK1

STK

Mobility Shift, IMAPTM

02-364

TSSK2

STK

Mobility Shift, IMAPTM

02-165

TSSK3

STK

Mobility Shift, IMAPTM

02-166

TTK

STK

ELISA

05-169

TXK

TK

Mobility Shift, IMAPTM

08-183

TYK2

TK

Mobility Shift, IMAPTM

08-147

TYRO3

TK

Mobility Shift, IMAPTM

08-109

WEE1

STK

ELISA

05-177

WNK1

STK

Mobility Shift, IMAPTM

05-179

WNK2

STK

Mobility Shift, IMAPTM

05-180

WNK3

STK

Mobility Shift, IMAPTM

05-181

YES (YES1)

TK

Mobility Shift, IMAPTM

08-175

YES (YES1) [T348I]

TK

Mobility Shift, IMAPTM

08-533

High [ATP] Kinase Panel

https://www.ntrc.nl/wp-content/uploads/2014/02/Kinome-Tree-Full-Panel_small.jpgThrough our partner Carna Biosciences we are offering the high [ATP] kinase panel. This panel facilitates inhibitor-type determinations (type I, II or III) by adding optional profiling at 1 mM ATP and kinase selectivity at physiological ATP levels.

https://www.ntrc.nl/wp-content/uploads/2014/02/Kinome-Tree-high-ATP_2.jpg
Kinases Available in the high [ATP] kinase panel

The high ATP kinase panel comprises 166 human kinases (107 TKs including mutants, 59 STKs) and allows the impact of ATP concentration on kinase-inhibitory activity to be rapidly visualized and assessed. Despite the sensitivity offered by performing in vitro assays at ATP concentrations approximating Km, physiological conditions are seldom the same. Inhibitory potency and selectivity may vary with the concentration of ATP available.

Target Name Group

Source

(Carna Cat No.)

ABL (ABL1) TK 08-001
ABL (ABL1) [T315I] TK 08-093
ABL (ABL1) [E255K] TK 08-094
ACK (TNK2) TK 08-196
AKT1 STK 01-101
ALK TK 08-518
ALK[F1174L] TK 08-519
ALK[L1196M] TK 08-529
ALK[R1275Q] TK 08-520
AMPK α1/β1/γ1 (PRKAA1/B1/G1) STK 02-113
ARG (ABL2) TK 08-102
AurA (AURKA) STK 05-101
AurB (AURKB)/INCENP STK 05-102
AurC (AURKC) STK 05-103
AXL TK 08-107
BLK TK 08-164
BMX TK 08-179
BRK (PTK6) TK 08-165
BRSK1 STK 02-115
BTK TK 08-080
CaMK4 STK 02-108
CDC2 /CycB1 STK 04-102
CDC7/ASK STK 05-109
CDK2 /CycE1 STK 04-165
CDK2 /CycA2 STK 04-103
CDK4 /CycD3 STK 04-105
CDK5 /p25 STK 04-106
CDK6 /CycD3 STK 04-107
CDK7 /CycH/MAT1 STK 04-108
CDK9 /CycT1 STK 04-110
CHK1 (CHEK1) STK 02-117
CHK2 (CHEK2) STK 02-162
CK1α (CSNK1A1) STK 03-101
CK1ε (CSNK1E) STK 03-104
CK2α1/β (CSNK2A1/B) STK 05-184
CSK TK 08-111
DAPK1 STK 02-134
DDR1 TK 08-113
DDR2 TK 08-114
DYRK1B STK 04-131
EGFR TK 08-115
EGFR[d746-750/T790M] TK 08-528
EGFR[d746-750] TK 08-527
EGFR[L858R] TK 08-502
EGFR[L861Q] TK 08-513
EGFR[T790M/L858R] TK 08-510
EGFR[T790M] TK 08-194
EML4-ALK TK 08-516
EPHA1 TK 08-119
EPHA2 TK 08-121
EPHA3 TK 08-122
EPHA4 TK 08-123
EPHA5 TK 08-124
EPHA6 TK 08-125
EPHA7 TK 08-126
EPHA8 TK 08-127
EPHB1 TK 08-128
EPHB2 TK 08-129
EPHB3 TK 08-130
EPHB4 TK 08-131
Erk1 (MAPK3) STK 04-142
Erk2 (MAPK1) STK 04-143
FAK (PTK2) TK 08-137
FER TK 08-139
FES TK 08-140
FGFR1 TK 08-133
FGFR2 TK 08-134
FGFR3 TK 08-135
FGFR3[K650E] TK 08-501
FGFR3[K650M] TK 08-199
FGFR4 TK 08-136
FGFR4[N535K] TK 08-524
FGFR4[V550E] TK 08-525
FGFR4[V550L] TK 08-526
FGR TK 08-166
FLT1 TK 08-189
FLT3 TK 08-154
FLT4 TK 08-190
FMS (CSF1R) TK 08-155
FRK TK 08-167
FYN TK 08-068
GSK3α (GSK3A) STK 04-140
GSK3β (GSK3B) STK 04-141
HCK TK 08-169
HER2 (ERBB2) TK 08-016
HER4 (ERBB4) TK 08-118
HGK (MAP4K4) STK 07-137
IGF1R TK 08-141
IKKβ (IKBKB) STK 05-084
INSR TK 08-142
IRR (INSRR) TK 08-143
ITK TK 08-181
JAK1 TK 08-144
JAK2 TK 08-045
JAK3 TK 08-046
JNK1 (MAPK8) STK 04-163
JNK2 (MAPK9) STK 04-164
JNK3 (MAPK10) STK 04-150
KDR TK 08-191
KIT TK 08-156
KIT[D816V] TK 08-505
KIT[T670I] TK 08-195
KIT[V560G] TK 08-504
KIT[V654A] TK 08-511
LCK TK 08-170
LTK TK 08-106
LYNa TK 08-171
LYNb TK 08-172
MAPKAPK2 STK 02-142
MER (MERTK) TK 08-108
MET TK 08-151
MET[Y1235D] TK 08-198
MST1 (STK4) STK 07-116
MUSK TK 08-153
NEK1 STK 05-123
NEK2 STK 05-226
NEK6 STK 05-130
NEK7 STK 05-131
NEK9 STK 05-133
NPM1-ALK TK 08-517
p38α (MAPK14) STK 04-152
p38β (MAPK11) STK 04-153
p38γ (MAPK12) STK 04-155
p38δ (MAPK13) STK 04-154
p70S6K (RPS6KB1) STK 01-154
PAK2 STK 07-124
PBK STK 05-168
PDGFRα (PDGFRA) TK 08-157
PDGFRα (PDGFRA) [T674I] TK 08-503
PDGFRα (PDGFRA) [V561D] TK 08-507
PDGFRβ (PDGFRB) TK 08-158
PDK1 (PDPK1) STK 01-132
PIM1 STK 02-054
PIM2 STK 02-155
PKACα (PRKACA) STK 01-127
PKCα (PRKCA) STK 01-133
PKCε (PRKCE) STK 01-136
PKD2 (PRKD2) STK 02-158
PLK1 STK 05-157
PLK3 STK 05-159
PYK2 (PTK2B) TK 08-138
RET TK 08-159
RET[G691S] TK 08-522
RET[M918T] TK 08-508
RET[S891A] TK 08-523
RET[Y791F] TK 08-521
ROCK1 STK 01-109
RON (MST1R) TK 08-152
ROS (ROS1) TK 08-163
RSK1 (RPS6KA1) STK 01-149
SGK STK 01-158
SRC TK 08-173
SRM (SRMS) TK 08-174
SYK TK 08-176
TEC TK 08-182
TIE2 (TEK) TK 08-185
TNK1 TK 08-104
TRKA (NTRK1) TK 08-186
TRKB (NTRK2) TK 08-187
TRKC (NTRK3) TK 08-197
TSSK1 STK 02-364
TXK TK 08-183
TYK2 TK 08-147
TYRO3 TK 08-109
YES (YES1) TK 08-175

QuickScout™ Cell Cycle Panel

Kinome-Tree-Quickscout_Cell-Cycle_smallThrough our partner Carna Biosciences we are offering QuickScout™ Cell Cycle Panel v2.0. This panel is comprised of relevant kinases for cell-cycle regulation and best for determining whether your compound acts on cell multiplication.

https://www.ntrc.nl/wp-content/uploads/2014/02/Kinome-Tree-Quickscout_Cell-Cycle_2.jpg
Kinases Available in QuickScout™ Cell Cycle panel

The QuickScout™ Cell Cycle Panel mainly includes kinases which are directly involved in the cell-cycle, and their inhibition may interfere with cell proliferation. Contact us to learn more about this panel and how we can help you identify the clinical potential of your compounds.

Target Name Group

Source

(Carna Cat No.)

AurA (AURKA) STK 05-101
AurB (AURKB)/INCENP STK 05-102
AurC (AURKC) STK 05-103
BRSK2 STK 02-116
CDC2 /CycB1 STK 04-102
CDC7/ASK STK 05-109
CDK2 /CycE1 STK 04-165
CDK2 /CycA2 STK 04-103
CDK3 /CycE1 STK 04-104
CDK4 /CycD3 STK 04-105
CDK6 /CycD3 STK 04-107
CDK7 /CycH/MAT1 STK 04-108
CDK9 /CycT1 STK 04-110
CHK1 (CHEK1) STK 02-117
CHK2 (CHEK2) STK 02-162
CK2 α1/β (CSNK2A1/B) STK 05-184
CK2 α2/β (CSNK2A2/B) STK 05-185
GSK3 β (GSK3B) STK 04-141
NEK1 STK 05-123
NEK2 STK 05-226
NEK6 STK 05-130
NEK7 STK 05-131
NEK9 STK 05-133
p38 α (MAPK14) STK 04-152
p70S6K (RPS6KB1) STK 01-154
PIM1 STK 02-054
PIM2 STK 02-155
PLK1 STK 05-157
PLK2 STK 05-158
RSK1 (RPS6KA1) STK 01-149

QuickScout™ STK Panel

Kinome-Tree-Quickscout_STK_smallThrough our partner Carna Biosciences we are offering the QuickScout™ STK Panel v2.0. This panel of 30 pre-selected Serine/Threonine kinases is comprised of key members from the AGC, CAMK, CMGC, STE, TKL, and Other Group of STK kinases.

https://www.ntrc.nl/wp-content/uploads/2014/02/Kinome-Tree-Quickscout_STK_2.jpg
Kinases Available in QuickScout™ STK panel

This panel allows you to screen your lead compounds using the industry’s most diverse Kinome Sampler and helps you discover and characterize the selectivity of your compounds as potential treatments for cancer, inflammatory, metabolic and/or neurological diseases. Contact us to learn more about this panel and how we can help you identify the clinical potential of your compounds.

Target Name Group

Source

(Carna Cat No.)

AKT1  STK 01-101  
AMPKα1/β1/γ1 (PRKAA1/B1/G1) STK 02-113  
AurA (AURKA) STK 05-101  
CaMK4  STK 02-108  
CDK2 /CycA2 STK 04-103  
CHK1 (CHEK1) STK 02-117  
CK1ε (CSNK1E) STK 03-104  
DAPK1  STK 02-134  
DYRK1B  STK 04-131  
Erk2 (MAPK1) STK 04-143  
GSK3β (GSK3B) STK 04-141  
HGK (MAP4K4) STK 07-137  
IKKβ (IKBKB) STK 05-084  
IRAK4  STK 09-145  
JNK2 (MAPK9) STK 04-164  
MAPKAPK2  STK 02-142  
MST1 (STK4) STK 07-116  
NEK2  STK 05-226  
p38α (MAPK14) STK 04-152  
p70S6K (RPS6KB1) STK 01-154  
PAK2  STK 07-124  
PBK  STK 05-168  
PDK1 (PDPK1) STK 01-132  
PIM1  STK 02-054  
PKACα (PRKACA) STK 01-127  
PKCα (PRKCA) STK 01-133  
PKD2 (PRKD2) STK 02-158  
ROCK1  STK 01-109  
SGK  STK 01-158  
TSSK1  STK 02-364  

QuickScout™ TK Panel

Kinome-Tree-Quickscout_TK_smallThrough our partner Carna Biosciences we are offering the QuickScout™ TK Panel v2.0. This panel of 20 pre-selected Tyrosine Kinases (TKs) is comprised of both receptor and non-receptor TKs and is offered to help you to rapidly screen your compounds against druggable and clinically relevant kinases.

https://www.ntrc.nl/wp-content/uploads/2014/02/Kinome-Tree-Quickscout_TK_2.jpg
Kinases Available in QuickScout™ TK panel

Identification and optimization of small molecular inhibitors against many of the targets in our 20 TK panel has led to the development of first and second generation therapeutics for the treatment of diseases such as leukemia and cancers of the lung, breast, and kidney. Contact us to learn more about this Panel and how we can help you identify the clinical potential of your compounds.

Target Name Group

Source

(Carna Cat No.)

ABL (ABL1) TK 08-001  
CSK  TK 08-111  
EGFR  TK 08-115  
EPHA2  TK 08-121  
EPHB4  TK 08-131  
FGFR1  TK 08-133  
FLT3  TK 08-154  
IGF1R  TK 08-141  
ITK  TK 08-181  
JAK3  TK 08-046  
KDR  TK 08-191  
LCK  TK 08-170  
MET  TK 08-151  
PDGFR α (PDGFRA) TK 08-157  
PYK2 (PTK2B) TK 08-138  
SRC  TK 08-173  
SYK  TK 08-176  
TIE2 (TEK) TK 08-185  
TRKA (NTRK1) TK 08-186  
TYRO3  TK 08-109